WebHerein, we prepared the multifunctional polyelectrolyte complex nanoparticles (CNPs), engineered by hyaluronic acid (HA) grafted polycaprolactone (PCL) nanoparticles (HA- g -PCL NPs) coated with chitosan (CS) electrostatically, as a platform to improve the oral delivery efficiency of lipophilic anticancer drugs. WebThis study aims to develop specific-molecular-weight hyaluronic acid oligosaccharides-coated paclitaxel-loaded casein nanoparticles (HA-PT-Cas NPs) via chemical …
Coating Solid Lipid Nanoparticles with Hyaluronic Acid Enhances ...
Web14 apr. 2024 · Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan that has a well-known ability to bind with the cluster of differentiation 44 (CD44) receptor on classically activated M1 macrophages. Resolving inflammation by varying the molecular weight of HA is a debated concept. Web10 jan. 2024 · We reported that hyaluronic acid (HA)-coated chitosan NPs promoted the drug delivery of 5-fluorouracil (5-Fu) into tumor cells that highly expressed CD44. Our … hypertherm xp45 manual
Development of propolis extract-loaded nanoparticles with …
WebCurrently, there is high interest in developing multifunctional theranostic platforms for cancer monitoring and chemotherapy. Herein, we report hyaluronan (HA)-coated … WebHA is a kind of natural acidic polysaccharide macromolecule; thus, it is generally regarded as biodegradable and nontoxic. 22 The overexpression of HA-binding receptor, such as CD44, has been found on the cell surface of some malignant tumors, which brings about the broad applications of HA-based NP in active tumor targeting for anticancer drugs. … Web30 sep. 2024 · Targeted delivery of hyaluronic acid-coated solid lipid nanoparticles for rheumatoid arthritis therapy. Drug Deliv. 25, 716–722 (2024). •• Highlights targeted drug … hypertherm xpr300 maintenance