WebAug 19, 2010 · However, citrinin H1, as a dimeric product formed upon heating at 140 • C in the presence of water, contributed to an increase in cytotoxicity [5]. Despite its toxic … WebJan 1, 2008 · However, Citrinin H1, another identified product of citrinin pyrolysis, also formed and is tenfold more toxic than citrinin (on a weight basis; Bentrivedi et al. 1993). γ-Aminobutyric acid Because the crude extract of MFR could alleviate hypertension in rats, a systematic fractionation and isolation of the responsible bioactive compound was ...
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Citrinin H1 is produced out of two citrinin molecules and its toxicity is increased compared to the original toxicity of citrinin. Citrinin H2, a formylated derivative of phenol A, is less toxic than citrinin. Phenol A seems to be produced mainly under acidic conditions. Dicitrinin A is a dimer of citrinin molecules … See more Citrinin is a mycotoxin which is often found in food. It is a secondary metabolite produced by fungi that contaminates long-stored food and it causes different toxic effects, like nephrotoxic, hepatotoxic and cytotoxic effects. … See more Citrinin was one of the many mycotoxins discovered by H. Raistrick and A.C. Hetherington in the 1930s. In 1941 H. Raistrick and G. Smith identified citrinin to have a broad antibacterial activity. After this discovery the interest in citrinin rose. However, in 1946 … See more The existing information on occurrence of citrinin in food suggests that relatively high citrinin concentrations can be found in stored grains and … See more Citrinin is biosynthesized by fungi species of Penicillium, Monascus and Aspergillus. For the production of citrinin, a minimal set of genes is needed. These genes are conserved in most … See more Citrinin is a polyketide mycotoxin, which is a secondary metabolite of some fungi species. Its IUPAC name is (3R,4S)-4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid and the molecular formula is C13H14O5. Citrinin has a … See more There are different types of toxicity. The types of toxicity that have been studied for citrinin are acute toxicity, nephrotoxicity, genotoxicity See more Various in vitro studies have revealed the involvement of citrinin toxicity in reduced cytokine production, inhibition of RNA and DNA synthesis, induction of oxidative stress, inhibition of nitride oxide gene expression, increase in ROS production and activation of … See more WebJan 2015. James Doughari Hamuel. Citrinin is a nephrotoxic mycotoxin produced by several fungal strains belonging to the genera Penicillium, Aspergillus and Monascus. It contaminates various ... how is gelatinase a virulence factor
Utilization of durian seed for Monascus fermentation and its ...
WebAnti-inflammatory Citrinin H1 Introduction Marine-derived fungi are known as a rich source of various bioactive metabolites with high range of chemical diver-sity. In the course of our ongoing research on the bioactive secondary metabolites from marine-derived fungal isolates (Lee et al. 2013; Quang et al. 2013, 2014; Kim et al. 2015), WebSep 14, 2024 · These components include citrinin, dicitrinin C, citreoisocoumarin, dihydrocitrinone, decarboxycitrinin, penicitrinone C, and others. The minimum inhibitory concentration (MIC) value of anti-T. vaginalis activity of citrinin was 200 µM. The marine fungi metabolites show potential as new alternatives to overcome drug resistance in T. … WebAug 26, 2006 · Two previously unreported citrinin dimer derivatives, penicitol D (1) and 1-epi-citrinin H1 (2), were isolated from the culture of a deep sea-derived fungus Penicillium citrinum NLG-S01-P1 ... how is geico home insurance rated